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peginesatide   Click here for help

GtoPdb Ligand ID: 7447

Synonyms: AF37702 | Hematide® | Omontys®
Approved drug
peginesatide is an approved drug (FDA (2012))
Compound class: Peptide
Comment: Peginesatide is a PEGylated functional analogue of erythropoietin.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Fan Q, Leuther KK, Holmes CP, Fong KL, Zhang J, Velkovska S, Chen MJ, Mortensen RB, Leu K, Green JM et al.. (2006)
Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia.
Exp Hematol, 34 (10): 1303-11. [PMID:16982323]
2. Macdougall IC, Wiecek A, Tucker B, Yaqoob M, Mikhail A, Nowicki M, MacPhee I, Mysliwiec M, Smolenski O, Sułowicz W et al.. (2011)
Dose-finding study of peginesatide for anemia correction in chronic kidney disease patients.
Clin J Am Soc Nephrol, 6 (11): 2579-86. [PMID:21940838]