- Advanced search
- Immuno Portal
- Malaria Portal
Synonyms: (+)-alpha-propoxyphene | Darvon® | propoxyphene
dextropropoxyphene is an approved drug
Compound class: Synthetic organic
Comment: Dextropropoxyphene is principally an opioid analgesic. Chemically it is an optical isomer of levopropoxyphene (the (2R,3S) optical isomer with PubChem CID 200742); dextropropoxyphene being the (2S,3R) enantiomer. Marketing in Europe and the US has been discontinued due to concerns of fatal overdoses and heart arrhythmias.
1. Xiao Y, Smith RD, Caruso FS, Kellar KJ. (2001)
Blockade of rat alpha3beta4 nicotinic receptor function by methadone, its metabolites, and structural analogs.
J. Pharmacol. Exp. Ther., 299 (1): 366-71. [PMID:11561100]