Ligand id: 7726

Name: AZD8165

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 131.15
Molecular weight 513.13
XLogP 3.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Karlsson S, Branalt J, Halvarsson MO, Bergman J. (2014)
A One-Pot Asymmetric Synthesis of a N ‑ Acylated 4,5- Dihydropyrazole, A Key Intermediate of Thrombin Inhibitor AZD8165.
Organic Process Research and Development, 18: 969-975.