Synonyms: histone deacetylase inhibitor VI
Compound class:
Synthetic organic
Comment: HNHA is a novel histone deacetylase (HDAC) inhibitor with potential anti-tumour and anti-liver fibrosis activity [1-2].
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References |
1. Kim DH, Lee J, Kim KN, Kim HJ, Jeung HC, Chung HC, Kwon HJ. (2007)
Anti-tumor activity of N-hydroxy-7-(2-naphthylthio) heptanomide, a novel histone deacetylase inhibitor. Biochem Biophys Res Commun, 356 (1): 233-8. [PMID:17353008] |
2. Park KC, Park JH, Jeon JY, Kim SY, Kim JM, Lim CY, Lee TH, Kim HK, Lee HG, Kim SM et al.. (2014)
A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic stellate cells. Br J Pharmacol, 171 (21): 4820-30. [PMID:24467283] |