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Synonyms: TARC | thymus- and activation-regulated chemokine
Compound class: Endogenous peptide in human, mouse or rat
Comment: CCL17 is a CC family cytokine.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Imai T, Chantry D, Raport CJ, Wood CL, Nishimura M, Godiska R, Yoshie O, Gray PW. (1998)
Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4.
J Biol Chem, 273 (3): 1764-8. [PMID:9430724]
2. Lee MC, Saleh R, Achuthan A, Fleetwood AJ, Förster I, Hamilton JA, Cook AD. (2018)
CCL17 blockade as a therapy for osteoarthritis pain and disease.
Arthritis Res Ther, 20 (1): 62. [PMID:29622035]