PF-4708671

Ligand id: 8036

Name: PF-4708671

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 60.94
Molecular weight 390.18
XLogP 3.06
No. Lipinski's rules broken 0

Molecular properties generated using the CDK
References
1. Pearce LR, Alton GR, Richter DT, Kath JC, Lingardo L, Chapman J, Hwang C, Alessi DR. (2010)
Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).
Biochem. J., 431 (2): 245-55. [PMID:20704563]