compound 10 [PMID: 23147077]

Ligand id: 8133

Name: compound 10 [PMID: 23147077]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 63.7
Molecular weight 359.17
XLogP 5.15
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Terao Y, Suzuki H, Yoshikawa M, Yashiro H, Takekawa S, Fujitani Y, Okada K, Inoue Y, Yamamoto Y, Nakagawa H et al.. (2012)
Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors.
Bioorg. Med. Chem. Lett., 22 (24): 7326-9. [PMID:23147077]