|
Synonyms: ENA-78
Compound class:
Endogenous peptide in human, mouse or rat
Comment: Bioactive CXCL5 is 78 aa in length, cleaved form a 114 aa presursor peptide. It can be N-terminally cleaved by cathepsin G and chymotrypsin to CXCL5-74 and CXCL5-70.
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
|
1. Ahuja SK, Murphy PM. (1996)
The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. J Biol Chem, 271 (34): 20545-50. [PMID:8702798] |
