CXCL7   Click here for help

GtoPdb Ligand ID: 830

Synonyms: PPBP
Immunopharmacology Ligand
Comment: CXCL7 (neutrophil-activating peptide 2, NAP-2) is one of the cleavage products of the pro-platelet basic protein (PPBP) gene. Connective tissue activating protein III and beta-thrombogulin are also products of this gene.
Species: Human
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1. Ahuja SK, Murphy PM. (1996)
The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor.
J Biol Chem, 271 (34): 20545-50. [PMID:8702798]