Synonyms: 4-phenylbutanoic acid | Ammonaps® | Buphenyl® | gamma-phenylbutyric acid | triButyrate
phenylbutyrate is an approved drug (FDA (1996), EMA (1999))
Compound class:
Synthetic organic
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References |
1. Gardian G, Browne SE, Choi DK, Klivenyi P, Gregorio J, Kubilus JK, Ryu H, Langley B, Ratan RR, Ferrante RJ et al.. (2005)
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease. J Biol Chem, 280 (1): 556-63. [PMID:15494404] |
2. Iannitti T, Palmieri B. (2011)
Clinical and experimental applications of sodium phenylbutyrate. Drugs R D, 11 (3): 227-49. [PMID:21902286] |
3. Ryu H, Smith K, Camelo SI, Carreras I, Lee J, Iglesias AH, Dangond F, Cormier KA, Cudkowicz ME, Brown Jr RH et al.. (2005)
Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice. J Neurochem, 93 (5): 1087-98. [PMID:15934930] |