IGN523   Click here for help

GtoPdb Ligand ID: 8737

Compound class: Antibody
Comment: IGN523 is a humanized anti-CD98 (SLC3A2) monoclonal antibody being investigated as a potential therapy for acute myeloid leukemia (AML) [1-2].
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1. Hayes GM, Chinn L, Cantor JM, Cairns B, Levashova Z, Tran H, Velilla T, Duey D, Lippincott J, Zachwieja J et al.. (2015)
Antitumor activity of an anti-CD98 antibody.
Int J Cancer, 137 (3): 710-20. [PMID:25556716]
2. Lippincott J, H van der Horst E, Zachwieja J, Tran H. (2013)
Anti-cd98 antibodies and methods of use thereof.
Patent number: WO2013078377 A1. Assignee: Igenica, Inc.. Priority date: 23/11/2011. Publication date: 30/05/2013.