Ligand id: 9174

Name: altiratinib

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 109.42
Molecular weight 510.15
XLogP 4.17
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Flynn DL, Kaufman MD, Smith BD. (2016)
Inhibition of tumor cell interactions with the microenvironment resulting in a reduction in tumor growth and disease progression.
Patent number: WO2016061231. Assignee: Deciphera Pharmaceuticals, Llc. Priority date: 14/10/2014. Publication date: 21/04/2016.