Ligand id: 9367

Name: LGB321

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 104.37
Molecular weight 457.17
XLogP 2.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Garcia PD, Langowski JL, Wang Y, Chen M, Castillo J, Fanton C, Ison M, Zavorotinskaya T, Dai Y, Lu J et al.. (2014)
Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers.
Clin. Cancer Res., 20 (7): 1834-45. [PMID:24474669]