compound 14n [PMID: 25589934]

Ligand id: 9423

Name: compound 14n [PMID: 25589934]

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 135.03
Molecular weight 418.04
XLogP 3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Halland N, Schmidt F, Weiss T, Saas J, Li Z, Czech J, Dreyer M, Hofmeister A, Mertsch K, Dietz U et al.. (2015)
Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors.
ACS Med Chem Lett, 6 (1): 73-8. [PMID:25589934]