navamepent

Ligand id: 9463

Name: navamepent

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 66.76
Molecular weight 304.17
XLogP 2.51
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Cholkar K, Gilger BC, Mitra AK. (2016)
Topical delivery of aqueous micellar resolvin E1 analog (RX-10045).
Int J Pharm, 498 (1-2): 326-34. [PMID:26706439]
2. Gjorstrup P, Schwartz CE. (2016)
Compositions and methods for the treatment of inflammation.
Patent number: US20140275247A1. Assignee: ANIDA PHARMA Inc. Priority date: 13/04/2013. Publication date: 19/04/2016.
3. Hesselink JM, Chiosi F, Costagliola C. (2016)
Resolvins and aliamides: lipid autacoids in ophthalmology - what promise do they hold?.
Drug Des Devel Ther, 10: 3133-3141. [PMID:27729772]
4. Torricelli AA, Santhanam A, Agrawal V, Wilson SE. (2014)
Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK.
Mol. Vis., 20: 1710-6. [PMID:25558174]