Ligand id: 9577

Name: AZ13102909

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 5
Rotatable bonds 12
Topological polar surface area 142.23
Molecular weight 543.3
XLogP 4.24
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Hasan M, Yan N. (2016)
Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies.
Pharmacol. Res., 111: 336-42. [PMID:27353409]
2. Vu HL, Aplin AE. (2014)
Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma.
Mol. Cancer Res., 12 (10): 1509-19. [PMID:24962318]