NNC1702   Click here for help

GtoPdb Ligand ID: 9760

Synonyms: des-His1-[Glu9, Lys24(4 X γGlu), Leu27]glucagon
Comment: Low-potency partial agonist, designed to have reduced agonist activity but to maintain relatively high binding affinity to the receptor [1].
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1. Zhang H, Qiao A, Yang L, Van Eps N, Frederiksen KS, Yang D, Dai A, Cai X, Zhang H, Yi C et al.. (2018)
Structure of the glucagon receptor in complex with a glucagon analogue.
Nature, 553 (7686): 106-110. [PMID:29300013]