PF-06684511

Ligand id: 9831

Name: PF-06684511

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 137.02
Molecular weight 435.12
XLogP 1.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Zhang L, Chen L, Dutra JK, Beck EM, Nag S, Takano A, Amini N, Arakawa R, Brodney MA, Buzon LM et al.. (2018)
Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.
J. Med. Chem., 61 (8): 3296-3308. [PMID:29356535]