Ligand id: 9838

Name: UFP-505

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 11
Topological polar surface area 124.76
Molecular weight 514.26
XLogP 2.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Dietis N, McDonald J, Molinari S, Calo G, Guerrini R, Rowbotham DJ, Lambert DG. (2012)
Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505).
Br J Anaesth, 108 (2): 262-70. [PMID:22194444]
2. Dietis N, Niwa H, Tose R, McDonald J, Ruggieri V, Filaferro M, Vitale G, Micheli L, Ghelardini C, Salvadori S et al.. (2018)
In vitro and in vivo characterization of the bifunctional μ and δ opioid receptor ligand UFP-505.
Br. J. Pharmacol., 175 (14): 2881-2896. [PMID:29524334]