Ligand id: 9921

Name: tafetinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 77.23
Molecular weight 424.23
XLogP 3.41
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Wang D, Tang F, Wang S, Jiang Z, Zhang L. (2012)
Preclinical anti-angiogenesis and anti-tumor activity of SIM010603, an oral, multi-targets receptor tyrosine kinases inhibitor.
Cancer Chemother. Pharmacol., 69 (1): 173-83. [PMID:21638122]