Ligand id: 9938

Name: pCXCL8-1aa

Structure and Physico-chemical Properties

2D Structure
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1. Falsone A, Wabitsch V, Geretti E, Potzinger H, Gerlza T, Robinson J, Adage T, Teixeira MM, Kungl AJ. (2013)
Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo.
Biosci. Rep., 33 (5). [PMID:23919527]
2. McNaughton EF, Eustace AD, King S, Sessions RB, Kay A, Farris M, Broadbridge R, Kehoe O, Kungl AJ, Middleton J. (2018)
Novel Anti-Inflammatory Peptides Based on Chemokine-Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis.
J. Immunol., 200 (9): 3201-3217. [PMID:29572348]
3. Proudfoot AE, Fritchley S, Borlat F, Shaw JP, Vilbois F, Zwahlen C, Trkola A, Marchant D, Clapham PR, Wells TN. (2001)
The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity.
J. Biol. Chem., 276 (14): 10620-6. [PMID:11116158]
4. Proudfoot AEI, Johnson Z, Bonvin P, Handel TM. (2017)
Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System.
Pharmaceuticals (Basel), 10 (3). [PMID:28792472]