Synonyms: compound 13 [PMID: 11170644]
Compound class:
Synthetic organic
Comment: Orita-13 is a prototypical inhibitor of the tautomerase activity of macrophage migration inhibitory factor (MIF) [2].
|
|
References |
1. Cisneros JA, Robertson MJ, Valhondo M, Jorgensen WL. (2016)
Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg Med Chem Lett, 26 (12): 2764-2767. [PMID:27156768] |
2. Orita M, Yamamoto S, Katayama N, Aoki M, Takayama K, Yamagiwa Y, Seki N, Suzuki H, Kurihara H, Sakashita H et al.. (2001)
Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography. J Med Chem, 44 (4): 540-7. [PMID:11170644] |