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Synonyms: VEGFA(138-165)
Compound class:
Peptide or derivative
Comment: This peptide corresponds to the exon 7-encoded neuropilin-1-binding site of VEGF165 [1]. It induces tumour cell and endothelial cell apoptosis via binding to neuropilin 1.
The peptide sequence was claimed in Ark Therapeutics' patent WO2003082918A1 that was granted in 2003 [2], in which EG3287 is noted as being a bicyclic form of Ac-SCKNTDSRCKARQLELNERTCRCDKPRR. |
Peptide Sequence  |
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| SCKNTDSRCKARQLELNERTCRCDKPRR-NH2 | |
| Ser-Cys-Lys-Asn-Thr-Asp-Ser-Arg-Cys-Lys-Ala-Arg-Gln-Leu-Glu-Leu-Asn-Glu-Arg-Thr-Cys-Arg-Cys-Asp-Lys-Pro-Arg-Arg-NH2 | |
