FUZS-5   Click here for help

GtoPdb Ligand ID: 12200

Synonyms: 5'-deoxy-5'-thiothymidine | 5'-Thiothymidine
PDB Ligand
Compound class: Synthetic organic
Comment: FUZS-5 is a thymidine nucleoside analogue. It has been found to interact with an allosteric site on the SARS-CoV-2 Nsp15 endoribonuclease [1].
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 123.12
Molecular weight 258.07
XLogP 0.36
No. Lipinski's rules broken 0
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Canonical SMILES SC[C@H]1O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=O
Isomeric SMILES Cc1cn(c(=O)[nH]c1=O)[C@H]1C[C@@H]([C@H](O1)CS)O
InChI InChI=1S/C10H14N2O4S/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(4-17)16-8/h3,6-8,13,17H,2,4H2,1H3,(H,11,14,15)/t6-,7+,8+/m0/s1
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Molecular structure representations generated using Open Babel