TSH   Click here for help

GtoPdb Ligand ID: 3920

Synonyms: Thyrogen® | thyroid-stimulating hormone | thyrotropin
Approved drug
TSH is an approved drug (FDA (1953))
Compound class: Endogenous peptide in human, mouse or rat
Comment: The drug thyrotropin alfa is a peptide heterodimer consisting of an α and β subunit and mimics the endogenous peptide hormone.
Species: Human
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: tsh

Subunits
TSH β subunit
glycoprotein hormone common alpha subunit
Peptide Sequence Click here for help
No information available.
Post-translational Modification
The production of biologically active TSH requires appropriately folded TSHβ and common α subunits that assemble to form the TSH heterodimer.