LIF   Click here for help

GtoPdb Ligand ID: 5016

Synonyms: cholinergic differentiation factor (CDF) | differentiation-inducing factor (DIF) | human interleukin in DA cells (HILDA)
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: LIF is an IL-6 family cytokine.
Species: Human
Peptide Sequence Click here for help
SPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKL
VELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKK
LGCQLLGKYKQIIAVLAQAF
Selected 3D Structures
PDB Id: 1LKI
Image of ligand 3D structure from RCSB PDB
Post-translational Modification
N-linked glycosylation of asparagine residues at positions 9, 34, 63, 73, 96 and 116; disulphide bond formation between cysteine residues at positions 12 and 134, 18 and 131, and 60 and 163