5-LOX activating protein   Click here for help

GtoPdb Ligand ID: 5183

Abbreviated name: FLAP
Synonyms: 5-lipoxygenase-activating protein | arachidonate 5-lipoxygenase-activating protein
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: FLAP is a scaffolding protein involved in leukotriene (eicosanoid proinflammatory mediator) biosynthesis. It has been investigated as a molecular target for novel anti-inflammatory drugs [3,5], in particular for airway inflammation [4,6].
Species: Human
Peptide Sequence Click here for help
MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQ
VPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLI
P