chlorambucil   Click here for help

GtoPdb Ligand ID: 7143

Synonyms: chlorbutin | Leukeran®
Approved drug PDB Ligand
chlorambucil is an approved drug (FDA (1957))
Compound class: Synthetic organic
Comment: Chlorambucil is a DNA alkylating agent.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 40.54
Molecular weight 303.08
XLogP 3.93
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES ClCCN(c1ccc(cc1)CCCC(=O)O)CCCl
Isomeric SMILES ClCCN(c1ccc(cc1)CCCC(=O)O)CCCl
InChI InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
InChI Key JCKYGMPEJWAADB-UHFFFAOYSA-N
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InChI standard key Download

Molecular structure representations generated using Open Babel