peptide KLK2b(c1)   Click here for help

GtoPdb Ligand ID: 8484

Compound class: Peptide
Comment: Peptide KLK2b(c1) is a selective inhibitor of glandular kallikrein (KLK2) [4], a testis-specific serine protease. KLK2 inhibitors are being investigated as novel therapeutics to prevent the metastasis of prostate cancer [1-3,5-7].
Peptide Sequence Click here for help
GCAARFKVWWAACG
Gly-Cys-Ala-Ala-Arg-Phe-Lys-Val-Trp-Trp-Ala-Ala-Cys-Gly
Chemical Modification
The peptide is cyclized by forming a disulphide bridge between the two cysteine residues.