SKA-121   Click here for help

GtoPdb Ligand ID: 8492

Synonyms: SKA 121 | SKA121
Compound class: Synthetic organic
Comment: SKA-121 has been shown to be a KCa3.1-specific positive gating modulator suitable for further exploring the therapeutic potential of KCa3.1 activation [1].
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 52.05
Molecular weight 198.08
XLogP 2.58
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES Nc1nc2c(o1)c1ccccc1c(c2)C
Isomeric SMILES Nc1nc2c(o1)c1ccccc1c(c2)C
InChI InChI=1S/C12H10N2O/c1-7-6-10-11(15-12(13)14-10)9-5-3-2-4-8(7)9/h2-6H,1H3,(H2,13,14)
Download 2D Structure Click here for help
Canonical SMILES Download
Isomeric SMILES Download
InChI standard identifier Download
InChI standard key Download

Molecular structure representations generated using Open Babel