RgIA4   Click here for help

GtoPdb Ligand ID: 9472

Compound class: Peptide
Comment: RgIA4 is an α-conotoxin RgIA derivative, designed for potential pain therapy. Functionally it is a potent and selective α9α10 nicotinic acetylcholine receptor (nAChR) antagonist [1].
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Peptide Sequence Click here for help
GlyCysCysThrAspProArgCysCitTyrGlnCysTyr
Chemical Modification
Tyr10 is monoido-Tyr; Cit is citrulline; disulphide bridges Cys1-Cys7 and Cys3-Cys12.