cefpimizole   Click here for help

GtoPdb Ligand ID: 10779

Synonyms: CPIZ | U 63196E | U-63,196 | U-63196E
Compound class: Synthetic organic
Comment: Cefpimizole (U 63196E) is a third-generation cephalosporin antibacterial with activity against Gram-positive and Gram-negative bacilli [1-2].
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 14
Hydrogen bond donors 5
Rotatable bonds 14
Topological polar surface area 276.55
Molecular weight 670.12
XLogP 0.92
No. Lipinski's rules broken 2
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Canonical SMILES O=C([C@@H](c1ccccc1)NC(=O)c1nc[nH]c1C(=O)O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C[n+]1ccc(cc1)CCS(=O)(=O)[O-]
Isomeric SMILES O=C([C@@H](c1ccccc1)NC(=O)c1nc[nH]c1C(=O)O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C[n+]1ccc(cc1)CCS(=O)(=O)[O-]
InChI InChI=1S/C28H26N6O10S2/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44)/t18-,21-,26-/m1/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
5464 cefpimizole
Synonyms Click here for help
CPIZ | U 63196E | U-63,196 | U-63196E
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Cefpimizole
Other databases
CAS Registry No. 84880-03-5 (source: WHO INN record)
ChEMBL Ligand CHEMBL2103902
DrugCentral Ligand 3075
GtoPdb PubChem SID 405560220
PubChem CID 68597
Search Google for chemical match using the InChIKey LNZMRLHZGOBKAN-KAWPREARSA-N
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UniChem Compound Search for chemical match using the InChIKey LNZMRLHZGOBKAN-KAWPREARSA-N
UniChem Connectivity Search for chemical match using the InChIKey LNZMRLHZGOBKAN-KAWPREARSA-N