levopropicillin   Click here for help

GtoPdb Ligand ID: 10826

Synonyms: BRL-284 | BRL284 | L-Propicillin | P-248 | P248
Compound class: Synthetic organic
Comment: Levopropicillin (levopropylcillin) is a penicillin type antibacterial, with activity against Staphylococci but it is not stable to penicillinase.
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 121.24
Molecular weight 378.12
XLogP 2.25
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES CC[C@@H](C(=O)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)O)(C)C)Oc1ccccc1
Isomeric SMILES CC[C@@H](C(=O)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)O)(C)C)Oc1ccccc1
InChI InChI=1S/C18H22N2O5S/c1-4-11(25-10-8-6-5-7-9-10)14(21)19-12-15(22)20-13(17(23)24)18(2,3)26-16(12)20/h5-9,11-13,16H,4H2,1-3H3,(H,19,21)(H,23,24)/t11-,12+,13-,16+/m0/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2S)-2-phenoxybutanoyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
International Nonproprietary Names Click here for help
INN number INN
1323 levopropicillin
Synonyms Click here for help
BRL-284 | BRL284 | L-Propicillin | P-248 | P248
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo levopropylcillin, L-Propicillin, BRL-284
Other databases
CAS Registry No. 3736-12-7 (source: WHO INN record)
ChEMBL Ligand CHEMBL3990988
GtoPdb PubChem SID 405560267
PubChem CID 172994
Search Google for chemical match using the InChIKey HOCWPKXKMNXINF-RSUWNVLCSA-N
Search Google for chemicals with the same backbone HOCWPKXKMNXINF
Search PubMed clinical trials levopropicillin
Search PubMed titles levopropicillin
Search PubMed titles/abstracts levopropicillin
UniChem Compound Search for chemical match using the InChIKey HOCWPKXKMNXINF-RSUWNVLCSA-N
UniChem Connectivity Search for chemical match using the InChIKey HOCWPKXKMNXINF-RSUWNVLCSA-N