tedizolid   Click here for help

GtoPdb Ligand ID: 10865

Synonyms: DA-7157 | previously torezolid | Sivextro® | TR-700 | TR700
Approved drug PDB Ligand
tedizolid is an approved drug (FDA (2014), EMA (2015))
Compound class: Synthetic organic
Comment: Tedizolid is an oxazolidinone antibacterial compound [1].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 106.26
Molecular weight 370.12
XLogP 1.9
No. Lipinski's rules broken 0
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Canonical SMILES OC[C@@H]1OC(=O)N(C1)c1ccc(c(c1)F)c1ccc(nc1)c1nnn(n1)C
Isomeric SMILES OC[C@@H]1OC(=O)N(C1)c1ccc(c(c1)F)c1ccc(nc1)c1nnn(n1)C
InChI InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2014), EMA (2015))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
9136 tedizolid
Synonyms Click here for help
DA-7157 | previously torezolid | Sivextro® | TR-700 | TR700
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Tedizolid (Sivextro)
Other databases
CAS Registry No. 856866-72-3 (source: WHO INN record)
ChEMBL Ligand CHEMBL1257051
DrugBank Ligand DB14569
GtoPdb PubChem SID 405560306
PubChem CID 11234049
Search Google for chemical match using the InChIKey XFALPSLJIHVRKE-GFCCVEGCSA-N
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UniChem Compound Search for chemical match using the InChIKey XFALPSLJIHVRKE-GFCCVEGCSA-N
UniChem Connectivity Search for chemical match using the InChIKey XFALPSLJIHVRKE-GFCCVEGCSA-N