balsalazide   Click here for help

GtoPdb Ligand ID: 11569

Synonyms: Colazal® | Colazide® | Giazo®
Approved drug
balsalazide is an approved drug (UK (1997), FDA (2000),)
Compound class: Synthetic organic
Comment: Balsalazide is a prodrug of the anti-inflammatory drug mesalazine.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 148.65
Molecular weight 357.1
XLogP 2.72
No. Lipinski's rules broken 0
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Canonical SMILES OC(=O)CCNC(=O)c1ccc(cc1)N=Nc1ccc(c(c1)C(=O)O)O
Isomeric SMILES OC(=O)CCNC(=O)c1ccc(cc1)N=Nc1ccc(c(c1)C(=O)O)O
InChI InChI=1S/C17H15N3O6/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (UK (1997), FDA (2000),)
Is prodrug? Yes
Active form mesalazine
IUPAC Name Click here for help
5-[[4-(2-carboxyethylcarbamoyl)phenyl]diazenyl]-2-hydroxybenzoic acid
International Nonproprietary Names Click here for help
INN number INN
5221 balsalazide
Synonyms Click here for help
Colazal® | Colazide® | Giazo®
Database Links Click here for help
CAS Registry No. 80573-04-2 (source: WHO INN record)
ChEMBL Ligand CHEMBL1208641
DrugBank Ligand DB01014
GtoPdb PubChem SID 441604941
PubChem CID 54585
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