cefozopran   Click here for help

GtoPdb Ligand ID: 12054

Synonyms: SCE-2787
Approved drug
cefozopran is an approved drug (Japan)
Compound class: Synthetic organic
Comment: Cefozopran is a fourth generation cephalosporin, belonging to the β-lactam class of antibacterial compounds. It has broad-spectrum activity and was developed by Takeda for parenteral treatment of infections caused by a range of Gram-positive and Gram-negative bacteria [1-2].
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 10
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 237.65
Molecular weight 515.08
XLogP -2.04
No. Lipinski's rules broken 0
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Canonical SMILES CO/N=C(/c1nsc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])C[n+]1ccn2c1cccn2
Isomeric SMILES CO/N=C(/c1nsc(n1)N)\C(=O)N[C@H]1[C@@H]2N(C1=O)C(=C(CS2)C[n+]1c2cccnn2cc1)C(=O)[O-]
InChI InChI=1S/C19H17N9O5S2/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32)/b24-11-/t12-,17-/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (Japan)
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6918 cefozopran
Synonyms Click here for help
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Cefozopran
Other databases
CAS Registry No. 113359-04-9 (source: Scifinder)
ChEMBL Ligand CHEMBL1276663
DrugBank Ligand DB13667
DrugCentral Ligand 551
GtoPdb PubChem SID 472319176
PubChem CID 9571080
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