Synonyms: Example 161 [WO2011153942A1]
Compound class:
Synthetic organic
Comment: We obtained the chemical structure for sacibertinib from the WHO's proposed INN list 127 (21 July 2022). In this document it was described as a tyrosine kinase inhibitor and antineoplastic. This same chemical structure is claimed in patent WO2011153942A1 [1]. Inventions of this patent are described as inhibitors of erbB family receptor tyrosine kinases, in particular of EGFR and Her2 (ERBB2).
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-[(3S)-oxolan-3-yl]oxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide |
International Nonproprietary Names | |
INN number | INN |
12300 | sacibertinib |
Synonyms |
Example 161 [WO2011153942A1] |
Database Links | |
CAS Registry No. | 1351941-69-9 (source: WHO INN record) |
GtoPdb PubChem SID | 472319212 |
PubChem CID | 89496273 |
Search Google for chemical match using the InChIKey | ZGYIXVSQHOKQRZ-COIATFDQSA-N |
Search Google for chemicals with the same backbone | ZGYIXVSQHOKQRZ |
Search PubMed clinical trials | sacibertinib |
Search PubMed titles | sacibertinib |
Search PubMed titles/abstracts | sacibertinib |
UniChem Compound Search for chemical match using the InChIKey | ZGYIXVSQHOKQRZ-COIATFDQSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | ZGYIXVSQHOKQRZ-COIATFDQSA-N |