pheneticillin   Click here for help

GtoPdb Ligand ID: 12275

Synonyms: alfacilin | Broxil® | feneticillin | phenethicillin
Approved drug
pheneticillin is an approved drug
Compound class: Synthetic organic
Comment: Pheneticillin is a penicillin belonging to the β-lactam class of antibacterial compounds.
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/). All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 121.24
Molecular weight 364.11
XLogP 1.89
No. Lipinski's rules broken 0

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

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Canonical SMILES CC(C(=O)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)O)(C)C)Oc1ccccc1
Isomeric SMILES CC(C(=O)N[C@H]1[C@@H]2N(C1=O)[C@H](C(S2)(C)C)C(=O)O)Oc1ccccc1
InChI InChI=1S/C17H20N2O5S/c1-9(24-10-7-5-4-6-8-10)13(20)18-11-14(21)19-12(16(22)23)17(2,3)25-15(11)19/h4-9,11-12,15H,1-3H3,(H,18,20)(H,22,23)/t9?,11-,12+,15-/m1/s1
InChI Key NONJJLVGHLVQQM-JHXYUMNGSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[2-(phenoxy)propanoylamino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
International Nonproprietary Names Click here for help
INN number INN
1011 pheneticillin
Synonyms Click here for help
alfacilin | Broxil® | feneticillin | phenethicillin
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Pheneticillin
Other databases
CAS Registry No. 147-55-7 (source: Scifinder)
ChEBI CHEBI:52427
ChEMBL Ligand CHEMBL1614637
DrugBank Ligand DB13337
DrugCentral Ligand 2124
GtoPdb PubChem SID 473153863
PubChem CID 272833
Search Google for chemical match using the InChIKey NONJJLVGHLVQQM-JHXYUMNGSA-N
Search Google for chemicals with the same backbone NONJJLVGHLVQQM
Search PubMed clinical trials pheneticillin
Search PubMed titles pheneticillin
Search PubMed titles/abstracts pheneticillin
UniChem Compound Search for chemical match using the InChIKey NONJJLVGHLVQQM-JHXYUMNGSA-N
UniChem Connectivity Search for chemical match using the InChIKey NONJJLVGHLVQQM-JHXYUMNGSA-N