prolgolimab   Click here for help

GtoPdb Ligand ID: 12991

Synonyms: BCD-100 | BCD100
Immunopharmacology Ligand
Compound class: Antibody
Comment: Prolgolimab (BCD-100) is a chimeric IgG1 anti-programmed cell death 1 (PD-1) monoclonal antibody [1]. It acts as an inhibitor of the PD-1/PD-L1-PD-L2 inhibitory immune checkpoint. The design of prolgolimab abolishes FcγR binding and therefore Fc-mediated effector functions (antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity).
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10904 prolgolimab
Synonyms Click here for help
BCD-100 | BCD100
Database Links Click here for help
GtoPdb PubChem SID 485206112
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