nurulimab   Click here for help

GtoPdb Ligand ID: 12992

Synonyms: BCD-145 | BCD145
Immunopharmacology Ligand
Compound class: Antibody
Comment: Nurulimab (BCD-145) is a human IgG1 anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA4) monoclonal antibody. It blocks the interaction between CTLA4 and its ligands CD80 and CD86, which establishes an inhibitory immune checkpoint. Blocking this checkpoint offers therapeutic potential as this mechanism stimulates the immune system to destroy cancer cells.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11141 nurulimab
Synonyms Click here for help
BCD-145 | BCD145
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 960
Other databases
GtoPdb PubChem SID 485206113
Search PubMed clinical trials nurulimab
Search PubMed titles nurulimab
Search PubMed titles/abstracts nurulimab