[Leu]enkephalin   Click here for help

GtoPdb Ligand ID: 1613

Synonyms: [Leu]-enkephalin | leucine enkephalin
Species: Human, Mouse, Rat
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2D Structure
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Canonical SMILES O=C(CNC(=O)C(Cc1ccc(cc1)O)N)NCC(=O)NC(C(=O)NC(C(=O)O)CC(C)C)Cc1ccccc1
Isomeric SMILES O=C(CNC(=O)C(Cc1ccc(cc1)O)N)NCC(=O)NC(C(=O)NC(C(=O)O)CC(C)C)Cc1ccccc1
InChI InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
IUPAC Name Click here for help
2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
Synonyms Click here for help
[Leu]-enkephalin | leucine enkephalin
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
PENK proenkephalin Human proenkephalin-A preproenkephalin
Penk preproenkephalin Mouse proenkephalin-A ENK, Penk, Penk1, PPA
Penk proenkephalin Rat proenkephalin-A Enk, enkephalin, MGC93514, Penk1, Penk2, Penk-rs, preproenkephalin 2, preproenkephalin, related sequence, proenkephalin, proenkephalin 1, proenkephalin 2, proenkephalin-A, proenkephalin related sequence, proenkephalin, related sequence
Database Links Click here for help
Specialist databases
GPCRdb Ligand [Leu]enkephalin
Other databases
BindingDB Ligand 50016831
CAS Registry No. 58822-25-6 (source: NCI)
ChEMBL Ligand CHEMBL15038
Ensembl Gene ENSG00000181195 (Hs), ENSRNOG00000008943 (Rn), ENSMUSG00000045573 (Mm)
GtoPdb PubChem SID 135651802
Human Protein Atlas ENSG00000181195 (Hs)
PubChem CID 3903
Search Google for chemical match using the InChIKey URLZCHNOLZSCCA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone URLZCHNOLZSCCA
UniChem Compound Search for chemical match using the InChIKey URLZCHNOLZSCCA-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey URLZCHNOLZSCCA-UHFFFAOYSA-N
UniProtKB P04094 (Rn), P22005 (Mm), P01210 (Hs)
Wikipedia Leu-enkephalin