memantine   Click here for help

GtoPdb Ligand ID: 4253

Synonyms: Axura® | Ebixa® | Namenda®
Approved drug
memantine is an approved drug (EMA (2002), FDA (2003))
Compound class: Synthetic organic
Comment: Memantine is a non-competitive NMDA receptor antagonist approved for Alzheimer's disease but is also being studied in non-dementia psychiatric disorders [1] .
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 26.02
Molecular weight 179.17
XLogP 3.52
No. Lipinski's rules broken 0
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Canonical SMILES CC12CC3CC(C1)(C)CC(C2)(C3)N
Isomeric SMILES CC12CC3CC(C1)(C)CC(C2)(C3)N
InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (EMA (2002), FDA (2003))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
3952 memantine
Synonyms Click here for help
Axura® | Ebixa® | Namenda®
Database Links Click here for help
CAS Registry No. 19982-08-2 (source: Scifinder)
DrugBank Ligand DB01043
DrugCentral Ligand 1679
GtoPdb PubChem SID 178101070
PubChem CID 4054
Search Google for chemical match using the InChIKey BUGYDGFZZOZRHP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BUGYDGFZZOZRHP
Search PubMed clinical trials memantine
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UniChem Compound Search for chemical match using the InChIKey BUGYDGFZZOZRHP-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey BUGYDGFZZOZRHP-UHFFFAOYSA-N
Wikipedia Memantine