Classification
Compound class	Synthetic organic

IUPAC Name

[(2R)-1-[(4-{3-[(benzenesulfonyl)methyl]-5-methylphenoxymethyl}phenyl)methyl]pyrrolidin-2-yl]methanol

Synonyms

compound 22a [PMID: 22397330] | PF 543 | sphingosine kinase 1 Inhibitor II

Comments

PF-543 is a selective inhibitor of sphingosine kinase-1 [2]. It is >100-fold selective for SphK1 over the SphK2 isoform.

Database Links
CAS Registry No.	1415562-82-1 (source: Scifinder)
ChEMBL Ligand	CHEMBL3134157
GtoPdb PubChem SID	178103236
PubChem CID	66577038
RCSB PDB Ligand	GYR
Search Google for chemical match using the InChIKey	NPUXORBZRBIOMQ-RUZDIDTESA-N
Search Google for chemicals with the same backbone	NPUXORBZRBIOMQ
Search UniChem for chemical match using the InChIKey	NPUXORBZRBIOMQ-RUZDIDTESA-N
Search UniChem for chemicals with the same backbone	NPUXORBZRBIOMQ
SynPHARM	78563 (in complex with sphingosine kinase 1)