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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
[(2R)-1-[(4-{3-[(benzenesulfonyl)methyl]-5-methylphenoxymethyl}phenyl)methyl]pyrrolidin-2-yl]methanol |
Synonyms ![]() |
compound 22a [PMID: 22397330] | PF 543 | sphingosine kinase 1 Inhibitor II |
Comments |
PF-543 is a selective inhibitor of sphingosine kinase-1 [2]. It is >100-fold selective for SphK1 over the SphK2 isoform. |
Database Links ![]() |
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CAS Registry No. | 1415562-82-1 (source: Scifinder) |
ChEMBL Ligand | CHEMBL3134157 |
GtoPdb PubChem SID | 178103236 |
PubChem CID | 66577038 |
RCSB PDB Ligand | GYR |
Search Google for chemical match using the InChIKey | NPUXORBZRBIOMQ-RUZDIDTESA-N |
Search Google for chemicals with the same backbone | NPUXORBZRBIOMQ |
Search UniChem for chemical match using the InChIKey | NPUXORBZRBIOMQ-RUZDIDTESA-N |
Search UniChem for chemicals with the same backbone | NPUXORBZRBIOMQ |
SynPHARM | 78563 (in complex with sphingosine kinase 1) |