terazosin   Click here for help

GtoPdb Ligand ID: 7302

Synonyms: ABBOTT-45975 | Hytrin®
Approved drug
terazosin is an approved drug (FDA (1987))
Compound class: Synthetic organic
Comment: Postsynaptic α1-adrenoceptor inhibitor.
Marketed formulations may contain terazosin hydrochloride (PubChem CID 44383).
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: terazosin

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 103.77
Molecular weight 387.19
XLogP 2.32
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES COc1cc2nc([nH]c(=N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1
Isomeric SMILES COc1cc2nc([nH]c(=N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1
InChI InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1987))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
4843 terazosin
Synonyms Click here for help
ABBOTT-45975 | Hytrin®
Database Links Click here for help
Specialist databases
GPCRdb Ligand terazosin
Other databases
CAS Registry No. 63590-64-7
DrugBank Ligand DB01162
DrugCentral Ligand 3584
GtoPdb PubChem SID 178103875
PubChem CID 5401
Search Google for chemical match using the InChIKey VCKUSRYTPJJLNI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VCKUSRYTPJJLNI
Search PubMed clinical trials terazosin
Search PubMed titles terazosin
Search PubMed titles/abstracts terazosin
UniChem Compound Search for chemical match using the InChIKey VCKUSRYTPJJLNI-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey VCKUSRYTPJJLNI-UHFFFAOYSA-N
Wikipedia Terazosin