ospemifene   Click here for help

GtoPdb Ligand ID: 7349

Synonyms: FC-1271 | Osphena® | Senshio®
Approved drug
ospemifene is an approved drug (FDA (2013), EMA (2015))
Compound class: Synthetic organic
Comment: Ospemifene is a selective estrogen receptor modulator (SERM) [2]. Like other SERMs it has mixed agonist/antagonist activities that are tissue-dependent.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 29.46
Molecular weight 378.14
XLogP 6.29
No. Lipinski's rules broken 1
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Canonical SMILES ClCCC(=C(c1ccccc1)c1ccc(cc1)OCCO)c1ccccc1
Isomeric SMILES ClCC/C(=C(\c1ccccc1)/c1ccc(cc1)OCCO)/c1ccccc1
InChI InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2013), EMA (2015))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
7859 ospemifene
Synonyms Click here for help
FC-1271 | Osphena® | Senshio®
Database Links Click here for help
CAS Registry No. 128607-22-7 (source: Scifinder)
ChEMBL Ligand CHEMBL2105395
DrugBank Ligand DB04938
DrugCentral Ligand 4749
GtoPdb PubChem SID 178103921
PubChem CID 3036505
Search Google for chemical match using the InChIKey LUMKNAVTFCDUIE-VHXPQNKSSA-N
Search Google for chemicals with the same backbone LUMKNAVTFCDUIE
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UniChem Compound Search for chemical match using the InChIKey LUMKNAVTFCDUIE-VHXPQNKSSA-N
UniChem Connectivity Search for chemical match using the InChIKey LUMKNAVTFCDUIE-VHXPQNKSSA-N
Wikipedia Ospemifene