Synonyms: Ro-109359 | Tegison®
etretinate is an approved drug (FDA (1986))
Compound class:
Synthetic organic
Comment: Etretinate is a highly lipophilic second-generation retinoid. Its use has largely been discontinued as it was discovered to be a long-acting teratogen, with detectable levels in plasma up to three years post-therapy.
![]() View more information in the IUPHAR Pharmacology Education Project: etretinate |
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1986)) |
Withdrawn drug? | Yes |
IUPAC Name ![]() |
ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate |
International Nonproprietary Names ![]() |
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INN number | INN |
4658 | etretinate |
Synonyms ![]() |
Ro-109359 | Tegison® |
Database Links ![]() |
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CAS Registry No. | 54350-48-0 |
ChEMBL Ligand | CHEMBL464 |
DrugBank Ligand | DB00926 |
DrugCentral Ligand | 1116 |
GtoPdb PubChem SID | 223365934 |
LIPID MAPS | LMPR01090046 |
PubChem CID | 5282375 |
Search Google for chemical match using the InChIKey | HQMNCQVAMBCHCO-DJRRULDNSA-N |
Search Google for chemicals with the same backbone | HQMNCQVAMBCHCO |
Search PubMed clinical trials | etretinate |
Search PubMed titles | etretinate |
Search PubMed titles/abstracts | etretinate |
UniChem Compound Search for chemical match using the InChIKey | HQMNCQVAMBCHCO-DJRRULDNSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | HQMNCQVAMBCHCO-DJRRULDNSA-N |
Wikipedia | Etretinate |