anifrolumab   Click here for help

GtoPdb Ligand ID: 8258

Synonyms: MDX-1333 | MEDI-546
Immunopharmacology Ligand
Compound class: Antibody
Comment: Anifrolumab is a monoclonal antibody targeting IFNAR1 (the receptor for α, β and ω interferons), being developed by the MedImmune subsidiary of AstraZeneca as a treatment for systemic lupus erythematosus (SLE).
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. [3]. Sequence BLAST using the heavy and light chain variable regions of anifrolumab provides 100% matches to sequences patented with application US7662381 [3]. The sequence matches identify anifrolumab as clone 11E2 in the patent.
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9800 anifrolumab
Synonyms Click here for help
MDX-1333 | MEDI-546
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 474
Other databases
GtoPdb PubChem SID 249565938
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Wikipedia Anifrolumab