liver enriched antimicrobial peptide 2   Click here for help

GtoPdb Ligand ID: 9734

Abbreviated name: LEAP2
Immunopharmacology Ligand
Comment: LEAP2 is an endogenous peptide with antimicrobial properties, that is part of the humoral immune response to microbes. It is expressed in the liver. LEAP2 has also been identified as an endogenous antagonist of the appetite-stimulatory hormone, ghrelin, that is secreted in the stomach and which acts via the pituitary/hypothalamic ghrelin receptor (growth hormone secretagogue receptor, or GHSR) [1].
Species: Human
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Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
LEAP2 liver enriched antimicrobial peptide 2 Human liver-expressed antimicrobial peptide 2 precursor LEAP-2, liver expressed antimicrobial peptide 2
Database Links Click here for help
Specialist databases
GPCRdb Ligand liver enriched antimicrobial peptide 2
Other databases
Ensembl Gene ENSG00000164406 (Hs)
GtoPdb PubChem SID 354702210
Human Protein Atlas ENSG00000164406 (Hs)
UniProtKB Q969E1 (Hs)