emicizumab   Click here for help

GtoPdb Ligand ID: 9744

Synonyms: ACE-910 | ACE910 | emicizumab-kxwh | Hemlibra® | RG6013
Approved drug
emicizumab is an approved drug (FDA (2017), EMA (2018))
Compound class: Antibody
Comment: Emicizumab, is a humanised bispecific antibody that binds blood coagulation factors IXa and X and acts as a factor VIII mimetic to bring about activation of factor X, and promote coagulation [2-3,5]. In essence, emicizumab works by bridging between coagulation factors IX and X and is the first-in-class drug for haemophilia A prevention with this mechanism of action.
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Classification Click here for help
Compound class Antibody
Approved drug? Yes (FDA (2017), EMA (2018))
International Nonproprietary Names Click here for help
INN number INN
10115 emicizumab
Synonyms Click here for help
ACE-910 | ACE910 | emicizumab-kxwh | Hemlibra® | RG6013
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 564
Other databases
GtoPdb PubChem SID 354702217
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