CZ415

Ligand id: 9837

Name: CZ415

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 87.76
Molecular weight 455.24
XLogP 3.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(4-{7,7-dimethyl-6,6-dimethylidene-4-[(3S)-3-methylmorpholin-4-yl]-5H,7H-6λ⁶-thieno[3,4-d]pyrimidin-2-yl}phenyl)-3-ethylurea
Synonyms
compound 3 [PMID: 27563401] | CZ-415
Comments
CZ415 is a potent and selective, ATP-competitive mTOR inhibitor that has potential anti-inflammatory activity [1].
Database Links
GtoPdb PubChem SID 363894131
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Search UniChem for chemical match using the InChIKey AQEVFCKBHLCDIP-INIZCTEOSA-N
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